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BAY-293 racemate
CAS No. 2244904-14-9
BAY-293 racemate( BAY293 racemate )
Catalog No. M13597 CAS No. 2244904-14-9
BAY-293 racemate (BAY293 racemate) is a potent SOS1 inhibitor that disrupts the KRAS-SOS1 interaction with IC50 of 50 nM。
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameBAY-293 racemate
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NoteResearch use only, not for human use.
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Brief DescriptionBAY-293 racemate (BAY293 racemate) is a potent SOS1 inhibitor that disrupts the KRAS-SOS1 interaction with IC50 of 50 nM。
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DescriptionBAY-293 racemate (BAY293 racemate) is a potent SOS1 inhibitor that disrupts the KRAS-SOS1 interaction with IC50 of 50 nM, the R-enantiomer (BAY-293) is the active form with IC50 of 21 nM, while the BAY-293 is less active (IC50=2,340 nM).
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In Vitro——
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In Vivo——
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SynonymsBAY293 racemate
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PathwayMAPK/ERK Signaling
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TargetRas
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RecptorRas
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Research Area——
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Indication——
Chemical Information
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CAS Number2244904-14-9
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Formula Weight448.585
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Molecular FormulaC25H28N4O2S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name6,7-dimethoxy-2-methyl-N-(1-(4-(2-((methylamino)methyl)phenyl)thiophen-2-yl)ethyl)quinazolin-4-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hillig RC, et al. Proc Natl Acad Sci U S A. 2019 Jan 25. pii: 201812963. doi: 10.1073/pnas.1812963116.
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